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Welcome all to "Is Pharmacology Difficult™️ podcast ". This is a Pharmacology podcast !! I am your host, Dr Radhika Vijay, M.B.B.S., M.D. Pharmacology, Sardar Patel Medical College, Bikaner, Rajasthan, India. Pharmacology (medical sciences) is my subject and I think Communicating about it to the masses is very essential. It is of great value and importance to every layman. The episodes here will be in simple English language (with few phrases and add ons of my favourite french language). The ...
 
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Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. "Il n'y a pas de raccourci pour aller la ou ca vaut la peine daller!" "There's no shortcut to get where it's worth going!" In today's episode, I will be covering details of the drug Atropine, its spectrum, its site of action, receptors and actions in detail! I will be doing th…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode , I will be heralding a new topic namely Anticholinergic/Antimuscarinic drugs. This is introductory episode for these agents. Atropine is hallmark/prototype drug and then I will be giving a long lively list of other drugs too! The main heads are Natural Alkaloi…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's talk, I will talk about both Stimulants and Blockers acting on Autonomic Ganglia. Names, mechanisms, details, indications, uses, etc. for both types will be discussed in detail. Short convo though, I will be hitting it out of the park!! For all the updates and lates…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Heading on to JUNE 5, the "World Environment Day," its the best time to take a pause and ponder over the discussions about Ecopharmacology or Environmental Pharmacology. Nothing more relevant than to have this celebrated "talk of the day". I will be covering 360 degree aspect …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode, I will discussing detail all about Anticholinesterase Poisoning, I will be covering all aspects of Organophosphate poisoning- agents, signs and symptoms, effects, non pharmacological treatment and medicinal therapy. Few small talks about Carbamate agent poison…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be conversing about Uses of Anticholinesterases in general. Actually it gonna be a list, and main uses talked about are - Lambert Eaton Syndrome, Cobra bite, Belladona poisoning, Alzheimer's disease, post operative Paralytic ileus and post operative …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, our curiosity rocket ship gonna fly high in space and sky of science and Erudition to explore all about Myasthenia Gravis, an Autoimmune disease/ Disorder. I will start with describing Autoimmune disease, then particularly Myasthenia Gravis, its pathogenesi…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's conversation, I will be detailing the Anticholinesterases , the Irreversible agents namely Carbamates, Carbaryl and Propoxur and Organophosphates, Malathion, Parathion, Dyflos, Ecothiophate, Isofluorophate, Tabun, Sarin, Soman. Everything from Classification, then m…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will be setting up the verbal conference about drug details, all reversible anticholinesterases like Physostigmine, Neostigmine, Pyridostigmine, Rivastigmine, Galantamine, Edrophonium, Ambenonium, Distigmine, Tacrine, Donepezil.... All sea waters gonna be …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today’s episode, I will be discussing Introductory aspects of Anticholinesterases, these are the inhibitors of Acetylcholine esterase enzyme which hydrolyses Acetylcholine in the synapse! It is all in all a new runway to land our plane of episode today… After discussing str…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today’s episode, I will be conveying details about Nicotine, its mechanism, etc. Though it is linked to the last episode and dosage forms of Nicotine Replacement Therapy (NRT) will not be repeated, an ample light is thrown on the toxicity, both acute and chronic toxicity of…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will continue the conversation from last session and cover two more Alkaloid Cholinergic drugs like Nicotine and Lobeline. And then the new talk will begin for the new day comprising of details about Choline esters which act directly on the muscarinic rec…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be detailing each and every Cholinergic Alkaloid Drug like Pilocarpine, Muscarine, Arecoline, Cevimiline, Tremorine and Oxotremorine. Along with the elaboration of details of these valuable gems, I will too discuss Mushroom poisoning (Mycetism) in de…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode i will be briefing the various cholinergic actions via Muscarinic and Nicotinic receptors and finally I will be getting my handle on the names of cholinergic Drugs or Cholinergic agonists. Wishing you all the colourful and best wishes during this festival ti…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode, initially with a quick glimpse of weather, I will talk about Nicotinic Cholinergic receptors. under this main head I will discuss their subtypes like Nm and Nn Nicotinic receptors, their site , their agonists and antagonists and major action, mechanism! For al…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will keep my parle embellished with details about Muscarinic Cholinergic Receptors found in Autonomic Nervous System (ANS). I will be grouping them both as per their significance and also on basis of their function or role. I will discuss all important he…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Heartiest thanks and congratulations for making upto 100th episode, it's a great, stupendous endeavour!! In today's episode I will be holding important conversations on All about Acetylcholine-it's synthesis, storage, release and degradation. I will be talking about all major …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, firstly I will summarize all we have known so far about Autonomic Nervous System (ANS) , in important bullet points, then I will discuss the Chemical signal interplay in ANS and finally I will be Introducing Cholinergic System or Parasympathetic system brie…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I would be setting my seal upon the Introductory talks about Autonomic Nervous System!! After telling few important exceptions to the general rules of ANS dual innervation, i will be briefing out the discussions about Co-Transmission and Non Adrenergic Non …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be drifting further the Introductory swings of ANS, I will furnish details about Enteric Nervous System and also highlight majorly the whole concept of Neurohumoral Pathway/Neurohumoral Transmission. For all the updates and latest episodes of my podc…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Continuing the trending legacy of ANS, today I will cover overview and brief introduction to Parasympathetic and Sympathetic Nervous System, details about the innervation, different ganglia involved and Neurotransmitters involved. Hope I keep up the interests to set your feet …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. BIEN VENUE 2022! I am here with a new season, a new episode numero uno namely Overview of Autonomic Nervous System (ANS) or Introduction to Autonomic Nervous System (ANS). In today's talk, I will be describing the introductory details of Central Nervous System (CNS) , its diff…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Bien Venue!! Welcome to the Season 2 Trailer of my Podcast. I will be telling you what we have covered in Season 1 and what we look forward to in Season 2. The essence lies in building blocks of the Castle of Pharmacology, the strong, sturdy anchorage it gonna provide to you a…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Well! Well! Well! This is the last episode of SEASON 1, and topic of the day is "Drug Antagonism" and YES! I kept my promise to talk about Affirmations for New Year too today!! Antagonism can be of many types like Chemical, Physiological and Pharmacological Antagonisms. Then I…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. With a good gracious planning to wave 2021 a "CHAO", let us prepare well for new chores in n ew year 2022. In today's episode I will talk about Drug Synergism, its subheads, types, and I will also cover Drug Selectivity, specificity, Therapeutic efficacy, therapeutic Index, (T…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. With the winters setting. in, I will be beginning today's episode in a poetic way and finally I will be setting up introduction to Dose Response relation/curves. Today I will cover the shape, importance of log DRC and its significance. I will be discussing three important aspe…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Today is a great Sunday as I am going to mark the end of receptor tale by discussing mainly two heads, namely No Receptor Mechanisms of Drug Action and also a few Receptor Pathologies. It will be a very informative talk and will be of great value at the same time great relief …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Marking the beginnings of today's episode, narrating the glory and essence of a LIBRARY, I will be talking about the Regulation of receptors. I will thoroughly explain the terms up regulation and down regulation of receptors. I will also talk about connected terms like superse…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. HAPPY DIWALI TO ALL!! In today's episode , I will be talking about enzyme linked and JAK-STAT Transmembrane receptors along with cytoplasmic and nuclear receptors. Season 1 coming to end, BUT BOOK OF SEASON 1 IS ON AMAZON Get your copy at: E-BOOK: https://www.amazon.in/dp/B09K…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode,I comment upon the details, structure and mechanism of Receptors which exist as ion channels. They have a special 5 subunit rosette structure ans function primarily via primary ligand modulation which binds to alpha subunit of the channel. For all the update…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. As a continuation of yester episode, today i will be discussing the three major effector pathways of G Protein Coupled Receptor , firstly the Adenylyl cyclase enzyme-cAMP pathway, then IP3-DAG Pathway, Ion channel regulation,... All will be explained with apt examples and deta…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will narrate the famous poem "Windows" by Wes Magee, communicate its amazing message and look into the window of today's topic i.e. G Protein coupled receptors. First and foremost a little word about the receptor nature and types, and then all about G prot…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be talking about Receptor drug occupation concept or rather to elaborate dual receptor nature! Receptor exists in two forms, "Ra" and "Ri". On this basis I will define Affinity and Efficacy concept which will further help to understand better the ter…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Wish you all a very happy international podcast day! Its for both listeners and creators. Together they ROCK!! Together they make podcast happen. Embellishing today's content with decor of sensible stats, I am thankful to all of you! For all the updates and latest episodes of …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Essence of Friendship is in "Sincerity" and "Frankness" of thoughts and words, else it becomes senseless. Today's dialogue is all about Receptor mechanisms of drug action. Actually we are starting it! Initially I will talk about about definition of receptors, and a few more te…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. First and Foremost, a little update from my end is to VOTE FOR MY PODCAST AT- https://www.community.hubhopper.com/hubhopper-awards For my podcast in "EDUCATIONAL PODCAST" Category. A little great expectations, a little request, always remember- One good deed deserves another!!…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Firstly its my great pleasure to wish all a very "HAPPY TEACHER'S DAY". Its a great day and yes I am here with a great discussion topic i.e. Enzyme Inhibition. First of all I will define as a ritual, then with no delay I will discuss its two main types, namely Competitive and …
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will be further stating the essence of Pharmacodynamics especially the introductory part! Initially I will be stating various drug mechanisms like Activation, Inhibition, Complexation and Neutralisation. All discussion is supported with examples, then I wi…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be introducing Pharmacodyamics, definition, concept, and try to cover as one line statement, two line statement!! To begin with, today's little contemplation about Criticism, how big deal is it?, how important and wisely you can deal with it, is it r…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. I welcome you all to make the podcast sound better cause its a Friday!! Singing the glory of being our best version throughout the week and a wish to start weekend afresh, I will introduce the topic of the day, its actually Therapeutic Drug Monitoring. As our custom, I will be…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Marking the celebrated beginnings with essence of birthdays of dear ones, i will quickly follow the ritual of announcing the topic of the day that resounds like Dosing Schedules. In this head, i will talk about drugs having real long half lives, that is more than 24 hours. Wha…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's I will be covering details about Dosing schedules. I will be narrating definition, aims and objectives, different conditions and states as far as duration of half lives are concerned. You will notice how importantly duration of half life affects the route of drug ad…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be emphasizing on the value of Wait, Patience and waiting for worthwhile things in life! That actually makes a lot of sense! The heading of today's talk dancing in fonts is the "plasma half life of drug". To start with, its a good ritual to define th…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will be emphasizing the essence and feel of returning home after long work hours or days out, its actually great and conveyed today in a quite melodious way!! Hope you all like it. Today's topic is Zero Order Elimination Kinetics. I will discuss the import…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Today I will be emphasizing on the upper hand power of listening over hearing! Yes, both are so different, we actually rarely listen!! Today, I want you all to listen to me. What are the different features of First order kinetics of elimination and what is the essence of knowi…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be emphasizing the hand in hand coordination of knowledge and wisdom. To start with, I will tell you the essence of knowledge of Drug elimination kinetics. I will define the topics and areas it covers, what all and why do we need to know it thoroughl…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I know the essence of French Open Tournament, wishing your favourite player the bestest of luck and wishes, if I am interrupting the score commentary, I do apologise, and promising a laconic set of colloque for the great Sunday, I break the ice with left ov…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. I will be starting today's episode with a beautiful thought compilation about "Lantern" and the book "Sky Lantern" by Matt Makeloto, its a lovely contemplation! Then i will cover the start of last route of Drug Elimination for our list and it is the Renal Excretion. Its the in…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's bonus episode, i will be covering a true bonus value topic about Drug dosage, there are 5 types that I will talk about, namely 1. Fixed Dose 2. Variable dose (with crude adjustments) 3. Variable dose (with fine adjustments) 4. Maximum tolerated dose 5. Minimum toler…
 
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will talk about the whole details, mechanics and essence of Elimination of drugs in breast milk. Why this knowledge is important? is the first question answered. Then I will discuss some physiological rules, mechanism of action governing it, all the proces…
 
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