A CYmPle Matter – CYP2C19 Polymorphisms and P2Y12 Inhibitor Selection in Ischemic Stroke
Manage episode 346535923 series 2908322
Jo Ann Leal, PharmD (Twitter: @jojopharmd) describes the implications of various CYP2C19 phenotypes on clopidogrel metabolism and activity, analyzes the available literature evaluating outcomes of clopidogrel versus ticagrelor in ischemic stroke patients based on CYP2C19 metabolizer status and selects a preferred antiplatelet agent and dose for secondary prevention of ischemic stroke given patient specific pharmacogenomic information.
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