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Sisällön tarjoaa Adam Buckingham. Adam Buckingham tai sen podcast-alustan kumppani lataa ja toimittaa kaiken podcast-sisällön, mukaan lukien jaksot, grafiikat ja podcast-kuvaukset. Jos uskot jonkun käyttävän tekijänoikeudella suojattua teostasi ilman lupaasi, voit seurata tässä https://fi.player.fm/legal kuvattua prosessia.
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112. Autonomous Trucks On US Roads in Q3, New Device Treats Pain Without Drugs, Starlink Gets FCC Green Light

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Jaa
 

Arkistoidut sarjat ("Toimeton syöte" status)

When? This feed was archived on March 29, 2024 08:06 (8h ago). Last successful fetch was on November 20, 2023 22:05 (4M ago)

Why? Toimeton syöte status. Palvelimemme eivät voineet hakea voimassa olevaa podcast-syötettä tietyltä ajanjaksolta.

What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.

Manage episode 333398202 series 2832936
Sisällön tarjoaa Adam Buckingham. Adam Buckingham tai sen podcast-alustan kumppani lataa ja toimittaa kaiken podcast-sisällön, mukaan lukien jaksot, grafiikat ja podcast-kuvaukset. Jos uskot jonkun käyttävän tekijänoikeudella suojattua teostasi ilman lupaasi, voit seurata tässä https://fi.player.fm/legal kuvattua prosessia.
News:

Cabless autonomous electric truck approved for US public roads | New Atlas (01:35)

  • Freight technology company Einride first introduced its cabless autonomous electric T-pod truck back in 2017.
    • Couple years later in 2020, it started rolling along Swedish Roads
    • Now the company has been given the green light for operation on public roads in the US.
  • In what Einride claims is a first, the National Highway Traffic Safety Administration (NHTSA) has approved its purpose-built autonomous electric vehicle to operate on public roads in the US, and there'll be no driver in the cab as the Einride Pod doesn't have a cab.
  • The T-pod Truck makes use of an onboard sensor suite:
    • cameras, radars and LiDARs
    • will be monitored remotely by a human operator
  • If you are curious about the sizing:
    • Each vehicle should measure about 7 meters (23 ft) in length, and be capable of carrying 15 standard pallets worth of cargo.
    • It will weigh 20 tons with a full load, covering a distance of approximately 200 km (124 miles) on one charge of its 200-kWh battery pack.
  • The public road pilot is due to start in Q3 of this year, where the vehicle will merge with existing fleet operations at a GE Appliances manufacturing facility.
    • Expected to move goods between warehouses and operate on public roads in mixed traffic.

Enzyme reverses muscle loss due to aging and cancer | The Bright Side News (05:25)

  • An international team led by uOttawa Faculty of Medicine researchers have published findings that could contribute to future therapeutics for muscle degeneration due to old age, and diseases such as cancer and muscular dystrophy.
  • Their work demonstrates the importance of the enzyme GCN5 in maintaining the expression of key structural proteins in skeletal muscle.
    • Those are the muscles attached to bone that breathing, posture and locomotion all rely on.
    • GCN5: a well-studied enzyme which regulates multiple cellular processes such as metabolism and inflammation.
  • Over the span of roughly five years, the uOttawa-led international collaboration painstakingly experimented with a muscle-specific mouse “knockout” of GCN5.
  • In this case, multiple experiments were done to examine the role the GCN5 enzyme plays in muscle fiber.
  • What they found:
    • A notable decline in muscle health during physical stress, such as downhill treadmill running, a type of exercise known by athletes to cause micro-tears in muscle fibers to stimulate muscle growth.
    • The affected mice became dramatically weaker as they scurried downhill, like those of old mice, while wild-type mice were not similarly impacted.
  • Dr. Menzies, the senior author of the study, says the findings are akin to what is observed in advanced aging, or myopathies and muscular dystrophy, a group of genetic diseases that result in progressive weakness and loss of muscle mass.
  • Ultimately, the team’s research found that GCN5 boosts the expression of key structural muscle proteins, notably dystrophin, and a lack of it will reduce them.
    • This is significant because dystrophin is the body’s most important protein for maintaining the membrane of muscle cells, serving as a kind of anchor and cushioning shock absorber in cells of muscles.
  • Dr. Menzies suggests the research could help to create a foundation for developing therapeutics down the line:
    • “These findings may therefore be useful for the discovery of new therapeutics that regulate GCN5 activity, or its downstream targets, for maintaining healthy muscle during cancer, myopathies, muscular dystrophy or aging,”

Scientists develop first-of-its-kind implant that relieves pain without drugs | Interesting Engineering (11:13)

  • Researchers at Northwestern University have developed a device that sounds straight out of science fiction: a small, soft, flexible first-of-its-kind implant that relieves pain on demand, without the use of drugs and dissolves.
    • Could provide a much-needed alternative to opioids and other highly addictive medications.
  • As per the researchers, the device could be highly valuable for patients who undergo routine surgeries or amputations that most often need post-operative medications.
  • Northwestern’s John A. Rogers, who led the device’s development, in a press release stated:
    • “As engineers, we are motivated by the idea of treating pain without drugs — in ways that can be turned on and off instantly, with user control over the intensity of relief. The technology reported here exploits mechanisms that have some similarities to those that cause your fingers to feel numb when cold. Our implant allows that effect to be produced in a programmable way, directly and locally to targeted nerves, even those deep within surrounding soft tissues.”
  • The device works by wrapping around nerves softly, to deliver precise and targeted cooling.
    • This in turn numbs nerves and blocks pain signals to the brain.
    • An external pump helps the user to remotely activate the device and control its intensity.
  • Once the device is no longer required, it is naturally absorbed into the body — "bypassing the need for surgical extraction".
  • Why does coolness help with pain?
    • Study co-author Dr. Matthew MacEwan of Washington University School of Medicine in St. Louis said that as nerves become cooler, the signals that travel through them become slower - eventually stopping completely.
    • “By delivering a cooling effect to just one or two targeted nerves, we can effectively modulate pain signals in one specific region of the body,"
  • The device contains tiny microfluidic channels to induce the cooling effect, while concurrently, a tiny integrated sensor monitors the temperature of the nerve to ensure that it doesn't get too cold, which could damage the tissue.
  • Rodgers talks on the monitoring:
    • "By monitoring the temperature at the nerve, the flow rates can be adjusted automatically to set a point that blocks pain in a reversible, safe manner. On-going work seeks to define the full set of time and temperature thresholds below which the process remains fully reversible."
  • At the thickness of a sheet of paper, the soft, elastic nerve cooling device is ideal for treating highly sensitive nerves.

Scientists Say New James Webb Images Are So Powerful That It Was Emotional Just Looking at Them | Futurism (18:25)

  • While we await the ceremonial release of the first official images taken by NASA's uber-expensive James Webb Space Telescope, early reactions to the long-awaited shots are already sounding pretty promising.
  • NASA's scientific missions lead Thomas Zurbuchen told reporters on Wednesday:
    • “The images are being taken right now… There is already some amazing science in the can, and some others are yet to be taken as we go forward. We are in the middle of getting the history-making data down."
  • NASA plans to release several images on July 12, the inaugural "first light" observations from the space telescope and a potentially groundbreaking moment for the field of astronomy.
  • Zurbuchen admitted he was in his feelings over the new images:
    • “It's really hard to not look at the universe in a new light and not just have a moment that is deeply personal … It's an emotional moment when you see nature suddenly releasing some of its secrets. and I would like you to imagine and look forward to that."
  • The images are expected to include unprecedented views of the depths of the universe and the atmosphere surrounding a distant exoplanet, potentially giving us glimpses of a habitable world other than our own.
  • It's the culmination of over a decade of research, and a $10 billion investment that could soon pay off in a big way.

Elon Musk's Starlink gets FCC green light to beam broadband into moving cars, planes, boats | Business Insider (21:56)

  • SpaceX won approval from the Federal Communications Commission to let its Starlink satellites send broadband internet to moving vehicles on Thursday.
    • Cleared a major hurdle as it has already signed deals with airline carriers including Hawaiian Airlines and exclusive jet firm JSX to provide in-flight WiFi to passengers.
  • "Authorizing a new class of terminals for SpaceX's satellite system will expand the range of broadband capabilities to meet the growing user demands that now require connectivity while on the move, whether driving an RV across the country, moving a freighter from Europe to a US port, or while on a domestic or international flight," the FCC said in its authorization order published Thursday.
  • The FCC's authorization will allow Starlink to pursue deals with transport companies more vigorously.
    • Royal Caribbean became the first cruise line to request Starlink on its ships in June.
  • Starlink also launched a $135 monthly subscription for RVs in May. At launch the company said the internet service could not be used while the RV was in motion.

  continue reading

100 jaksoa

Artwork
iconJaa
 

Arkistoidut sarjat ("Toimeton syöte" status)

When? This feed was archived on March 29, 2024 08:06 (8h ago). Last successful fetch was on November 20, 2023 22:05 (4M ago)

Why? Toimeton syöte status. Palvelimemme eivät voineet hakea voimassa olevaa podcast-syötettä tietyltä ajanjaksolta.

What now? You might be able to find a more up-to-date version using the search function. This series will no longer be checked for updates. If you believe this to be in error, please check if the publisher's feed link below is valid and contact support to request the feed be restored or if you have any other concerns about this.

Manage episode 333398202 series 2832936
Sisällön tarjoaa Adam Buckingham. Adam Buckingham tai sen podcast-alustan kumppani lataa ja toimittaa kaiken podcast-sisällön, mukaan lukien jaksot, grafiikat ja podcast-kuvaukset. Jos uskot jonkun käyttävän tekijänoikeudella suojattua teostasi ilman lupaasi, voit seurata tässä https://fi.player.fm/legal kuvattua prosessia.
News:

Cabless autonomous electric truck approved for US public roads | New Atlas (01:35)

  • Freight technology company Einride first introduced its cabless autonomous electric T-pod truck back in 2017.
    • Couple years later in 2020, it started rolling along Swedish Roads
    • Now the company has been given the green light for operation on public roads in the US.
  • In what Einride claims is a first, the National Highway Traffic Safety Administration (NHTSA) has approved its purpose-built autonomous electric vehicle to operate on public roads in the US, and there'll be no driver in the cab as the Einride Pod doesn't have a cab.
  • The T-pod Truck makes use of an onboard sensor suite:
    • cameras, radars and LiDARs
    • will be monitored remotely by a human operator
  • If you are curious about the sizing:
    • Each vehicle should measure about 7 meters (23 ft) in length, and be capable of carrying 15 standard pallets worth of cargo.
    • It will weigh 20 tons with a full load, covering a distance of approximately 200 km (124 miles) on one charge of its 200-kWh battery pack.
  • The public road pilot is due to start in Q3 of this year, where the vehicle will merge with existing fleet operations at a GE Appliances manufacturing facility.
    • Expected to move goods between warehouses and operate on public roads in mixed traffic.

Enzyme reverses muscle loss due to aging and cancer | The Bright Side News (05:25)

  • An international team led by uOttawa Faculty of Medicine researchers have published findings that could contribute to future therapeutics for muscle degeneration due to old age, and diseases such as cancer and muscular dystrophy.
  • Their work demonstrates the importance of the enzyme GCN5 in maintaining the expression of key structural proteins in skeletal muscle.
    • Those are the muscles attached to bone that breathing, posture and locomotion all rely on.
    • GCN5: a well-studied enzyme which regulates multiple cellular processes such as metabolism and inflammation.
  • Over the span of roughly five years, the uOttawa-led international collaboration painstakingly experimented with a muscle-specific mouse “knockout” of GCN5.
  • In this case, multiple experiments were done to examine the role the GCN5 enzyme plays in muscle fiber.
  • What they found:
    • A notable decline in muscle health during physical stress, such as downhill treadmill running, a type of exercise known by athletes to cause micro-tears in muscle fibers to stimulate muscle growth.
    • The affected mice became dramatically weaker as they scurried downhill, like those of old mice, while wild-type mice were not similarly impacted.
  • Dr. Menzies, the senior author of the study, says the findings are akin to what is observed in advanced aging, or myopathies and muscular dystrophy, a group of genetic diseases that result in progressive weakness and loss of muscle mass.
  • Ultimately, the team’s research found that GCN5 boosts the expression of key structural muscle proteins, notably dystrophin, and a lack of it will reduce them.
    • This is significant because dystrophin is the body’s most important protein for maintaining the membrane of muscle cells, serving as a kind of anchor and cushioning shock absorber in cells of muscles.
  • Dr. Menzies suggests the research could help to create a foundation for developing therapeutics down the line:
    • “These findings may therefore be useful for the discovery of new therapeutics that regulate GCN5 activity, or its downstream targets, for maintaining healthy muscle during cancer, myopathies, muscular dystrophy or aging,”

Scientists develop first-of-its-kind implant that relieves pain without drugs | Interesting Engineering (11:13)

  • Researchers at Northwestern University have developed a device that sounds straight out of science fiction: a small, soft, flexible first-of-its-kind implant that relieves pain on demand, without the use of drugs and dissolves.
    • Could provide a much-needed alternative to opioids and other highly addictive medications.
  • As per the researchers, the device could be highly valuable for patients who undergo routine surgeries or amputations that most often need post-operative medications.
  • Northwestern’s John A. Rogers, who led the device’s development, in a press release stated:
    • “As engineers, we are motivated by the idea of treating pain without drugs — in ways that can be turned on and off instantly, with user control over the intensity of relief. The technology reported here exploits mechanisms that have some similarities to those that cause your fingers to feel numb when cold. Our implant allows that effect to be produced in a programmable way, directly and locally to targeted nerves, even those deep within surrounding soft tissues.”
  • The device works by wrapping around nerves softly, to deliver precise and targeted cooling.
    • This in turn numbs nerves and blocks pain signals to the brain.
    • An external pump helps the user to remotely activate the device and control its intensity.
  • Once the device is no longer required, it is naturally absorbed into the body — "bypassing the need for surgical extraction".
  • Why does coolness help with pain?
    • Study co-author Dr. Matthew MacEwan of Washington University School of Medicine in St. Louis said that as nerves become cooler, the signals that travel through them become slower - eventually stopping completely.
    • “By delivering a cooling effect to just one or two targeted nerves, we can effectively modulate pain signals in one specific region of the body,"
  • The device contains tiny microfluidic channels to induce the cooling effect, while concurrently, a tiny integrated sensor monitors the temperature of the nerve to ensure that it doesn't get too cold, which could damage the tissue.
  • Rodgers talks on the monitoring:
    • "By monitoring the temperature at the nerve, the flow rates can be adjusted automatically to set a point that blocks pain in a reversible, safe manner. On-going work seeks to define the full set of time and temperature thresholds below which the process remains fully reversible."
  • At the thickness of a sheet of paper, the soft, elastic nerve cooling device is ideal for treating highly sensitive nerves.

Scientists Say New James Webb Images Are So Powerful That It Was Emotional Just Looking at Them | Futurism (18:25)

  • While we await the ceremonial release of the first official images taken by NASA's uber-expensive James Webb Space Telescope, early reactions to the long-awaited shots are already sounding pretty promising.
  • NASA's scientific missions lead Thomas Zurbuchen told reporters on Wednesday:
    • “The images are being taken right now… There is already some amazing science in the can, and some others are yet to be taken as we go forward. We are in the middle of getting the history-making data down."
  • NASA plans to release several images on July 12, the inaugural "first light" observations from the space telescope and a potentially groundbreaking moment for the field of astronomy.
  • Zurbuchen admitted he was in his feelings over the new images:
    • “It's really hard to not look at the universe in a new light and not just have a moment that is deeply personal … It's an emotional moment when you see nature suddenly releasing some of its secrets. and I would like you to imagine and look forward to that."
  • The images are expected to include unprecedented views of the depths of the universe and the atmosphere surrounding a distant exoplanet, potentially giving us glimpses of a habitable world other than our own.
  • It's the culmination of over a decade of research, and a $10 billion investment that could soon pay off in a big way.

Elon Musk's Starlink gets FCC green light to beam broadband into moving cars, planes, boats | Business Insider (21:56)

  • SpaceX won approval from the Federal Communications Commission to let its Starlink satellites send broadband internet to moving vehicles on Thursday.
    • Cleared a major hurdle as it has already signed deals with airline carriers including Hawaiian Airlines and exclusive jet firm JSX to provide in-flight WiFi to passengers.
  • "Authorizing a new class of terminals for SpaceX's satellite system will expand the range of broadband capabilities to meet the growing user demands that now require connectivity while on the move, whether driving an RV across the country, moving a freighter from Europe to a US port, or while on a domestic or international flight," the FCC said in its authorization order published Thursday.
  • The FCC's authorization will allow Starlink to pursue deals with transport companies more vigorously.
    • Royal Caribbean became the first cruise line to request Starlink on its ships in June.
  • Starlink also launched a $135 monthly subscription for RVs in May. At launch the company said the internet service could not be used while the RV was in motion.

  continue reading

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