Parhaat Culture Development Podcastit (2025)

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117: Critical Bottlenecks and Breakthroughs in Cell Line Development with Andrea Gough - Part 1 23:33

1d ago23:33

23:33

Send us a text Cell line development (CLD) is a cornerstone of biologics production. This intricate process involves establishing a cell line capable of consistently producing a desired product, such as a therapeutic protein. While advancing science has refined numerous aspects of CLD, bottlenecks still exist, perpetuating challenges for scientists…

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116: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy Agresti - Part 2 16:43

21d ago16:43

16:43

Send us a text The intersection of artificial intelligence and biology presents immense opportunities for transforming bioprocess development. As the biotech industry continues to evolve, data-driven innovations are critical to optimizing biologics manufacturing. High-quality datasets stand at the forefront of this transformation, empowering resear…

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115: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy Agresti - Part 1 19:49

23d ago19:49

19:49

Send us a text Bioprocess development is transforming the biotech industry, driving innovations in life-changing therapies. Success hinges on simplifying complex mechanisms and adopting advanced technologies. By integrating high-throughput screening and artificial intelligence, we can streamline workflows, reduce trial-and-error, and speed up biolo…

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114: Weighing of Single-Use Bag Systems: Why Traditional Load Cells Are Holding You Back with Anders Tvegaard - Part 2 18:08

28d ago18:08

18:08

Send us a text Is your bioprocess facility wasting precious time and resources on traditional weighing system calibrations? In this eye-opening episode, Anders Tvegaard, COO of Eilersen Electric, reveals how digital load cell innovation is revolutionizing bioprocess monitoring and validation. Discover why weighing systems aren't the commodity techn…

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113: Weighing of Single-Use Bag Systems: Why Traditional Load Cells Are Holding You Back with Anders Tvegaard - Part 1 22:22

30d ago22:22

22:22

Send us a text What do furniture manufacturing and bioprocess weighing have in common? In this fascinating episode, Anders Tvegaard, COO of Eilersen Electric Digital Systems shares the remarkable story of how his company evolved from solving a furniture maker's wood humidity measurement problems to revolutionizing pharmaceutical manufacturing. Fift…

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112: AI Meets Biology: Why Domain Expertise Still Rules in the Age of Large Language Models with Lars Brandén - Part 2 23:41

1M ago23:41

23:41

Send us a text Can artificial intelligence revolutionize drug development and reduce the staggering 90% failure rate in clinical trials? In this insightful episode, Lars Brandén, Director of Biology at Kolibri, shares his vision for the future of personalized medicine. Drawing from his extensive experience bridging academia and industry, Lars explo…

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111: AI Meets Biology: Why Domain Expertise Still Rules in the Age of Large Language Models with Lars Brandén - Part 1 19:08

1M ago19:08

19:08

Send us a text In this episode, we explore the delicate dance between artificial intelligence and biological research with Lars Brandén, Director of Biology at Kolibri. From his early fascination with gene therapy to pioneering high-throughput screening centers at prestigious institutions, Lars shares invaluable insights on bridging the gap between…

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110: Spinning Like Earth: Designing Low-Shear Bioreactors for Better Cell Culture with Olivier Detournay - Part 2 16:24

1M ago16:24

16:24

Send us a text Could Earth's gentle movements hold the key to scaling up cell therapy production? In this fascinating episode, cellular biologist and entrepreneur Olivier Detournay (CSO of Cellura) reveals how his groundbreaking bioreactor design, inspired by geophysics, is transforming difficult cell culture processes. By mimicking natural planeta…

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109: Spinning Like Earth: Designing Low-Shear Bioreactors for Better Cell Culture with Olivier Detournay - Part 1 19:27

1M ago19:27

19:27

Send us a text What if the secret to growing sensitive cells lies in mimicking Earth's own movement? In this fascinating episode, cellular biologist Olivier Detournay, CSO of Cellura, reveals how studying planetary motion led to a groundbreaking bioreactor design that could transform cell therapy manufacturing. Drawing inspiration from geophysics r…

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108: From 1 Billion to 100: How AI is Cracking the Enzyme Discovery Code with David Schönauer - Part 2 26:35

2M ago26:35

26:35

Send us a text In this captivating episode, we dive deep into the groundbreaking intersection of artificial intelligence and enzyme engineering with David Schönauer, founder and CEO of Aminoverse. From university lab benches to pioneering AI-driven enzyme discovery, David shares how his startup is transforming the biotech landscape by making enzyme…

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107: From 1 Billion to 100: How AI is Cracking the Enzyme Discovery Code with David Schönauer - Part 1 19:11

2M ago19:11

19:11

Send us a text Ever wondered how scientists find the perfect enzyme among billions of possibilities? In this fascinating episode of the Smart Biotech Scientist podcast, host David Brühlmann sits down with David Schönauer, CEO of Aminoverse, who's revolutionizing enzyme engineering through artificial intelligence. As a biotech entrepreneur who trans…

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106: From Proteins to Cell Therapy: Why ATMPs Aren't Just Complex Biologics with Oliver Kraemer - Part 2 19:51

2M ago19:51

19:51

Send us a text In this insightful episode, Technical Development Leader at Flagship Pioneering Oliver Kraemer reveals why developing Advanced Therapy Medicinal Products (ATMPs) require a fundamental shift in thinking from traditional biologics development. Drawing from his extensive experience across Boehringer Ingelheim, Sanofi, and BMS, Kraemer c…

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105: From Proteins to Cell Therapy: Why ATMPs Aren't Just Complex Biologics with Oliver Kraemer - Part 1 21:52

2M ago21:52

21:52

Send us a text In this eye-opening episode, we explore the intricate landscape of Advanced Therapy Medicinal Products (ATMPs) with Oliver Kraemer, a technical development leader at Flagship Pioneering. Drawing from his extensive experience at industry giants like BMS, Sanofi, and Boehringer Ingelheim, Oliver challenges conventional wisdom about aut…

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104: One-Stop Shop vs. Specialist CDMO: A Scientist's Guide to CDMO Selection with Sigma Mostafa - Part 2 17:17

2M ago17:17

17:17

Send us a text Want to peek behind the curtain of a leading Contract Development and Manufacturing Organization (CDMO)? In this inspiring episode, KBI Biopharma's Chief Scientific Officer Sigma Mostafa reveals the intricate world of bioprocess development and manufacturing. Sigma shares game-changing insights into accelerating biologics development…

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103: One-Stop Shop vs. Specialist CDMO: A Scientist's Guide to CDMO Selection with Sigma Mostafa - Part 1 24:01

2M ago24:01

24:01

Send us a text In this insightful episode, we're joined by Sigma Mostafa, Chief Scientific Officer at KBI Biopharma, who shares crucial insights on selecting the right CDMO partner for biotech development. Sigma brings a unique blend of scientific rigor and practical experience to the discussion, having worked on both sides of the CDMO relationship…

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102: PAT Revolution: Decoding Your Bioprocess Like Never Before with Katharina Dahlmann - Part 2 15:17

2M ago15:17

15:17

Send us a text Struggling to unravel the complexities of your bioprocess? Prepare for a paradigm shift as we dive into the world of Process Analytical Technology (PAT) with Katharina Dahlmann who is Application and PAT Expert at Hamilton. This eye-opening episode dissects how PAT is redefining biologics manufacturing, balancing its immense potentia…

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101: PAT Revolution: Decoding Your Bioprocess Like Never Before with Katharina Dahlmann - Part 1 23:12

2M ago23:12

23:12

Send us a text Unlock the hidden potential of your bioprocess! In this eye-opening episode, David Brühlmann sits down with Katharina Dahlmann, Application and PAT Expert at Hamilton, to explore the game-changing world of Process Analytical Technology (PAT). Discover how PAT is revolutionizing biotech by providing unprecedented insights into cell be…

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100: From Raw Data to Actionable Insights: Unlocking the Power of Process Models with Fabian Feidl - Part 2 18:01

3M ago18:01

18:01

Send us a text Imagine predicting your bioprocess outcomes as easily as checking the weather forecast. Sound impossible? Not anymore. In this insightful episode, we dive deep into the world of digital twins and process models with Fabian Feidl, co-founder and CTO of DataHow. Discover how these cutting-edge tools are reshaping the biotech landscape,…

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99: From Raw Data to Actionable Insights: Unlocking the Power of Process Models with Fabian Feidl - Part 1 22:00

3M ago22:00

22:00

Send us a text Are you ready to decode the future of bioprocessing? In this eye-opening episode, we dive deep into the world of digital bioprocess development with Fabian Feidl, co-founder and CTO of DataHow. Discover how cutting-edge process models are transforming the biotech industry, bridging the gap between raw data and actionable insights. Ke…

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98: The Biomanufacturing Revolution: Bringing Game-changing Products to Market with James Ryall - Part 2 17:59

3M ago17:59

17:59

Send us a text Are you ready to dive into the cutting-edge world of biomanufacturing? In this episode, strategic consultant James Ryall unveils the staggering potential of bio-based products to revolutionize industries. From cultured meat to human breast milk, discover how cells are becoming the ultimate manufacturing facilities. James shares inval…

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97: The Biomanufacturing Revolution: Bringing Game-changing Products to Market with James Ryall - Part 1 24:24

3M ago24:24

24:24

Send us a text In this captivating episode, host David Brühlmann welcomes James Ryall, a strategic consultant with over two decades of experience in cell biology and regenerative medicine. From his groundbreaking work in skeletal muscle research to revolutionizing cultured meat production, James shares his fascinating journey through academia and i…

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96: AI in Bioprocess Development: The Game-Changer You Can't Ignore with Belma Alispahic - Part 2 19:53

3M ago19:53

19:53

Send us a text Are you ready to revolutionize your bioprocess development? Join David Brühlmann as he interviews Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode, who unveils the game-changing potential of AI in biopharma. Discover how AI is transforming the industry, from drug discovery to manufacturing, and learn why it's …

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95: AI in Bioprocess Development: The Game-Changer You Can't Ignore with Belma Alispahic - Part 1 20:37

3M ago20:37

20:37

Send us a text Is AI the secret weapon biotech scientists have been waiting for? In this eye-opening episode, we dive deep into the world of AI-driven bioprocess development with Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode. Discover how AI is transforming the biotech landscape, from reducing downtime by 50% to unlocking…

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94: From Lab Coat to LinkedIn: Benjamin McLeod's Journey to Cell and Gene Therapy Influencer - Part 2 19:31

3M ago19:31

19:31

Send us a text In this electrifying episode, we dive deep into the future of biotech with biotech influencer Benjamin McLeod. From quantum AI mapping cellular interactions to the game-changing potential of process analytical technology, Ben, who is also a Cell & Gene Therapy Segment Lead at NanoMosaic, unveils how artificial intelligence is set to …

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Revolutionizing Lactation Spaces: Insights from Abbey Donnell of Work and Mother 23:50

3M ago23:50

23:50

On today's episode of the NextGen Work Culture podcast, we dive deep into the world of supporting working mothers with our special guest, Abbey Donnell, the founder and CEO of Work and Mother. Abbey shares her journey from recognizing a critical gap in workplace facilities for breastfeeding mothers to creating fully-equipped and managed lactation s…

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93: From Lab Coat to LinkedIn: Benjamin McLeod's Journey to Cell and Gene Therapy Influencer - Part 1 24:04

3M ago24:04

24:04

Send us a text Discover how a failed optometry dream led Benjamin McLeod to become a leading voice in cell and gene therapy. In this eye-opening episode, Ben, who is a Cell & Gene Therapy Segment Lead at NanoMosaic, shares his unconventional path from lab work to LinkedIn stardom, revealing how he bridges the gap between R&D and marketing in biotec…

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92: Mass Transfer Secrets: Mastering Bubbles and kLa from Bench to Large-Scale Production with Lars Puiman & Rik Volger - Part 2 16:29

3M ago16:29

16:29

Send us a text Ever wondered why your perfectly optimized lab process falls apart at industrial scale? Mass transfer experts Lars Puiman and Rik Volger from the University of Delft reveal the hidden world of oxygen transfer and aeration that can make or break your production. Dive into the crucial differences between lab-scale and industrial-scale …

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91: Mass Transfer Secrets: Mastering Bubbles and kLa from Bench to Large-Scale Production with Lars Puiman & Rik Volger - Part 1 16:37

4M ago16:37

16:37

Send us a text Unlock the mysteries of oxygen transfer in bioreactors with mass transfer experts Lars Puiman and Rik Volger from the University of Delft. In this eye-opening episode, dive deep into the crucial world of kLa (oxygen mass transfer coefficient) and its impact on bioprocess scale-up. Discover why understanding kLa is essential for optim…

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90: Scale-Up Secrets: Cracking the Code of AAV Production with Ahmed Youssef - Part 2 25:14

4M ago25:14

25:14

Send us a text Dive into the cutting-edge world of gene therapy as we unravel the complexities of AAV production. In this insightful episode, Ahmed Youssef, a seasoned AAV expert and Senior Process Development Manager at Ascend, explains how you can navigate the complex world of AAV scale-up and learn why thinking outside the box is crucial for suc…

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Revolutionizing Work-Life Balance for Parents with Sundays: A Conversation with Ashley Chang 22:23

4M ago22:23

22:23

Today we're joined by Ashley Chang, co-founder and CEO of Sundays, an innovative executive assistant service for working parents. Tune in as Ashley shares how Sundays aims to give parents the time they need to balance meaningful careers and family life. From discussing the gaps in workplace support for parents to innovative solutions like Sundays, …

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89: Scale-Up Secrets: Cracking the Code of AAV Production with Ahmed Youssef - Part 1 20:08

4M ago20:08

20:08

Send us a text Unlock the mysteries of AAV manufacturing in this eye-opening episode! Ahmed, a seasoned AAV expert and Senior Process Development Manager at Ascend, reveals insider strategies for biotech scientists navigating the complex world of gene therapy production. Discover why quality is the cornerstone of successful AAV development and how …

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88: The Swiss Army Knife of Biotech: Unleashing the Power of Fractional Expertise 16:38

4M ago16:38

16:38

Send us a text Unlock the secret weapon of biotech success! In this eye-opening episode, host David Brühlmann reveals how fractional CTOs are revolutionizing drug development, inspired by Michael Jordan's approach to greatness. Learn how this innovative strategy can slash timelines, mitigate risks, and give your biotech company a competitive edge. …

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87: The Hidden Pitfalls of Bioprocess Development: Lessons from the Trenches 16:54

4M ago16:54

16:54

Send us a text Unlock the secrets of successful bioprocess development with host David Brühlmann as he shares hard-won lessons from his 15+ years of experience leading technology transfers and technology innovation projects. Discover why prioritizing process development is crucial for transforming groundbreaking science into life-changing therapies…

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86: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo Morbidelli - Part 2 23:01

4M ago23:01

23:01

Send us a text What if your biomanufacturing facility could run itself, optimize its own processes, and operate non-stop? This isn't science fiction – it's the cutting-edge reality Professor Massimo Morbidelli is helping to create. In this captivating episode, the bioprocessing pioneer unveils how AI, continuous manufacturing, and revolutionary mac…

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The Struggles of a Working Caregiver – A Personal Perspective 9:15

4M ago9:15

9:15

In this solo episode, Kortney is diving into an often overlooked topic—working caregivers. Last week, we had an insightful conversation on this topic, and today Kortney shares her own family's journey through this challenging landscape. Her mom became the sole caregiver for her elderly parents, which drastically affected her ability to maintain a f…

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85: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo Morbidelli - Part 1 24:04

4M ago24:04

24:04

Send us a text Imagine a world where biologic drugs are produced faster, cheaper, and with unprecedented precision. In this episode, we dive into that future with Professor Massimo Morbidelli, a trailblazer in bioprocessing innovation. As a Professor Emeritus at ETH Zurich and Politecnico di Milano, and a co-founder of ChromaCon (now YMC) and DataH…

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84: The Hidden Potential of Shake Flasks: What Every Biotech Scientist Needs to Know with Jens Bayer - Part 2 23:17

4M ago23:17

23:17

Send us a text Are your shake flasks holding back your bioprocess development? Discover how to transform them into smart bioreactors! In this game-changing episode, we talk with Jens Bayer about the groundbreaking DOTS platform. He is a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientifi…

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The Expensive Consequences When Companies Fail Working Parents 10:08

4M ago10:08

10:08

Host Kortney Ross dives deep into the significant costs businesses face when they lack proper support structures for working parents, particularly those dealing with pregnancy and lactation-related issues. Kortney highlights startling statistics and shares real-world examples to illustrate just how much organizations can lose—both financially and i…

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83: The Hidden Potential of Shake Flasks: What Every Biotech Scientist Needs to Know with Jens Bayer - Part 1 18:25

4M ago18:25

18:25

Send us a text Are shake flasks outdated relics or untapped goldmines of bioprocess development? In this eye-opening episode, we dive deep with Jens Bayer, a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientific Bioprocessing. Jens shatters common misconceptions about shake flasks, reveal…

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82: Regenerating Muscles: The Future of Autologous Cell-based Therapy with Deana Mohr - Part 2 17:58

5M ago17:58

17:58

Send us a text Dive into the cutting-edge world of autologous cell-based therapy with Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich. In this eye-opening episode, discover how MUVON Therapeutics’ innovative approach to muscle regeneration is revolutionizing treatments for stress urinary incontinence and…

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Balancing Care Logistics and Work with Dovetail: A Conversation with Ashley Blackington 28:18

5M ago28:18

28:18

This episode covers the crucial topic of supporting working caregivers with guest Ashley Blackington, the CEO and founder of Dovetail. In this conversation, she sheds light on the unique challenges caregivers face, whether they're juggling childcare, elder care, or both. We explore how caregiving impacts employees in the workplace, the importance o…

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#129: Navigating Non-Linear Leadership | with Milica Wojno 31:03

5M ago31:03

31:03

How are you adapting your leadership style to meet the evolving needs of today's workforce? Join hosts J.R. and Lucas Flatter as they discuss the evolving landscape of leadership with guest Milica Wojno, a professional services leader from Australia. This insightful conversation explores the challenges of modern leadership, particularly the generat…

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81: Regenerating Muscles: The Future of Autologous Cell-based Therapy with Deana Mohr - Part 1 22:35

5M ago22:35

22:35

Send us a text Discover how scientists are transforming lives through innovative muscle regeneration therapy. In this captivating episode, Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich, unveils her groundbreaking autologous muscle regeneration technology for treating stress urinary incontinence. Learn …

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80: Think Before You Build: Holistic Approaches to Biotech Facility Design with Alfredo Martínez Mogarra - Part 2 20:14

5M ago20:14

20:14

Send us a text Ever wondered why some biotech facilities thrive while others struggle Alfredo Martínez Mogarra, a Bioprocess Engineer with over 30 years of experience and Chief Operations Manager at VIVEbiotech, reveals the secrets to successful biotech manufacturing. In this eye-opening episode, Alfredo shares critical insights on bridging the gap…

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Parenthood via Adoption: Boomie Odumade’s Insights on How Workplaces Can Support Adoptive Parents 33:38

5M ago33:38

33:38

This episode dives into parenting through adoption and the essential role of workplace support. Joining us is Boomie Odumade, a software engineering leader and adoptive parent. She shares her journey through domestic adoption, from navigating long wait times to the joys of bonding with her son. Boomie discusses balancing work with preparing for par…

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