Parhaat Nucleic Podcastit (2024)

1
The value of community – your microbiome 31:58

16d ago31:58

31:58

The history of fermented foods like beer, bread, and other foods can be traced back thousands of years to ancient civilizations in China and Egypt. This ancient technology was originally used to preserve foods when refrigeration was not an option. While less common in modern industrialized civilizations, we’re now realizing that fermented foods pla…

1
Therapeutic nucleic acids – a CDMO’s view on mRNA 32:04

2M ago32:04

32:04

While some of us knew a good bit about mRNA prior to 2020, we all got a crash course on mRNA technology and its prophylactic and therapeutic potential as a result of the COVID pandemic and subsequent SARS CoV-2 vaccine development. In fact, most of us have now received at least one mRNA vaccine at this point. Our guest for this episode, Dr. Christi…

1
A molecular thermometer for the future 35:29

3M ago35:29

35:29

There are all sorts of molecular tests to tell if you’re infected with something specific, but what do you use when you’re not sure what you might have? You might use a thermometer as a first step, but wouldn’t it be nice if that thermometer was a bit more high tech? In this episode we meet Dr. Nick Meyerson, CEO and co-founder of Darwin Bioscience…

1
Directed evolution – A PETase project 32:58

4M ago32:58

32:58

Plastics are a modern miracle of science that have helped deliver both convenience and life-saving solutions. However, we must now grapple with the challenge of immense amounts of plastics in our waste streams and environment. How do we best deconstruct plastics to reusable or more bio-friendly molecules? This is the exact challenge being addressed…

1
Scientific marketing in the century of the biotech revolution 32:37

5M ago32:37

32:37

Most scientists start their education and careers with a vision of working in the lab to discover great things and drive innovation. However, we don’t all end up loving the actual lab work portion of science. What non-lab career options exist to utilize molecular biology knowledge and skills? Well, according to our guest, Jason Amsbaugh, Founder an…

1
Cheers to molecular Biology 34:47

6M ago34:47

34:47

While the end product is quite different, brewing beer is not all that different than many other bioproduction processes used in the lab and industry. Both require skills, experience, and the right QC/QA methods to control and monitor the starting materials and the entire process, all the way to that bottle of suds you might be thirsty for. Steve a…

1
Unsung heroes of food health and safety 32:10

7M ago32:10

32:10

When you buy chicken or turkey from the grocery store, you might not give it much thought, but there is an entire network of people working to ensure the health of the animals in our food supply chain and your health. In this episode, we talk with an unsung hero, Beverly Wood, supervisor of the molecular diagnostics lab at the North Carolina Depart…

1
Molecular Biology for hire – the CRO experience 31:53

8M ago31:53

31:53

Contract Research Organizations (CROs) are a resource that most scientists know about but relatively few have first-hand, internal experience with. In this episode our hosts speak with Saboor Hekmaty, Director of Laboratory Operations at Avrok Biosciences, who pulls back the curtain to illuminate what CROs do, and the skills required for them to be…

1
High-throughput transcriptomics and AI for drug discovery 31:56

9M ago31:56

31:56

Doing something complex and meaningful in a new way requires thinking and acting a bit differently. This is the case with how Dr. Joey Azofeifa, from Arpeggio Bio, is using systems biology to discover new drug candidates. Join us in this Season 2 kickoff episode where we dive headlong into transcriptomics, systems biology, machine learning, and lea…

1
Season 2 Teaser 2:40

9M ago2:40

2:40

We start the second season of this series with an update on what you can expect from new episodes, which start to drop soon. Your host, Steve Lewis, shares details on changes you can expect as the series evolves. One change will be a broadening of application topics to be covered, as this season will include episodes discussing transcriptomics in b…

1
A look into the fruit bowl of biology 30:56

1y ago30:56

30:56

In this episode of Speaking of Mol Bio, we speak with Dr. Mandovi Chatterjee about single cell analysis. Dr. Chatterjee is the Director of Single Cell Core at Harvard University Medical School. She has spent her career at the exploring and mastering a wide variety of single cell methods . In conversation with Dr. Chatterjee, our hosts dive into the…

1
The intersection of biology and technology 38:45

1y ago38:45

38:45

In this episode, the hosts have an intriguing discussion with Dr. Ben Sun, Head of Biomarker Genetics at Biogen. Dr. Sun holds an MD/PhD from the University of Cambridge, providing a view and perspective on data from both research and clinical perspectives. The advantage of his unique background is that it provides a balanced perspective on large-s…

1
Multi-omics | The molecular biology of plants in space 31:59

1+ y ago31:59

31:59

Dr. Stan Roux, Professor of Molecular Biosciences at the University of Texas – Austin, has had a long and successful career based on his fascination with plants and his desire to understand plant biology. He’s spent his career exploring the effect of apyrase on root systems, crop yields, and plant nutrient uptake. We get into Stan’s unlikely career…

1
CRISPR | An insider’s perspective on CRISPR 31:39

1+ y ago31:39

31:39

In this episode, Gabriel and Steve welcome a colleague of theirs, Dr. Doris Beylkin, to share her depth of knowledge and perspective on the CRISPR cell engineering topic. While Doris is a Global Market Development Manager today, she has over 10 years of experience supporting customers in planning, troubleshooting, and analyzing gene modulation and …

1
Exosomes | The early realization of the exosome’s potential 32:11

1+ y ago32:11

32:11

This discussion with Dr. Johan Skog covers a lot of ground while staying super approachable. The Founder and Chief Scientific Officer of Exosome Diagnostics, starts by sharing basics about exosomes and tells us about how he’s translated his curiosity for the vesicles from tumor stem cells into his current role where he’s helped develop the world’s …

1
Lighting the touch paper for next generation nucleic acid therapies 32:06

1+ y ago32:06

32:06

In this episode Mike Ward, Clarivate’s Head of Thought Leadership for Life sciences and healthcare, spoke to Johnny Ohlson, Founder of Touchlight, a company who has developed a novel synthetic DNA vector. In recent years, we've seen that by harnessing the power of DNA, it has been possible to achieve success in treating previously incurable heredit…

1
Exosomes | Exploring the body’s extracellular delivery system 32:09

1+ y ago32:09

32:09

It’s been 40 years since extracellular vesicles, or exosomes, were first connected to the way cells communicate and transfer information. Since then, researchers have studied what part they play in the normal physiology of a cell. There has also been an expanding amount of work in the role that exosomes can play in therapeutics and diagnostics of a…

1
Multi-omics | Investigating the body’s internet 33:01

1+ y ago33:01

33:01

Multi-omics is a great example of how the scientific community is thinking larger and using complementary methods to gather deeper information to understand biology and inform medicine. Proteomics is just one of the -omes of multi-omics but it’s the one that Steve Williams, Chief Medical Officer at SomaLogic, has over 30 years’ experience in. Steve…

1
Multi-omics | The importance of science in data science 33:21

1+ y ago33:21

33:21

In this episode, we talk with Chris Whelan about the data behind science. Chris is the Director of Neuroscience, Data Science & Digital Health for Research and Development at The Janssen Pharmaceutical Companies of Johnson & Johnson, as well as the Chair of the UK Biobank Pharma Proteomics project. He connects the dots between genomics and proteomi…

1
CRISPR | Making the world better 29:57

2y ago29:57

29:57

Since it’s discovery, CRISPR Cas9 gene editing technology has blossomed and boomed. It’s moved from a highly technical niche technique to one that is arguably mainstream and being applied to countless challenges in applied biology. In this episode we talk with Travis Hardcastle, who previously worked in R&D to develop gene editing products and is n…

1
Season I Trailer 3:02

2y ago3:02

3:02

Experience the Speaking of Mol Bio podcast in its extended video format for a more immersive journey, while also ensuring accessibility with downloadable transcripts for each episode. Watch now at thermofisher.com/podcast-video A short trailer to introduce the Speaking of Mol Bio co-hosts and get their take on what the series is all about. You'll h…

1
Realizing the patient-friendly future of clinical trials 23:02

2+ y ago23:02

23:02

In this episode of Conversations in Healthcare, Ergomed founder Dr. Miroslav Reljanović talks to Mike Ward about how the COVID-19 pandemic has nudged clinical trials towards greater efficiency and inclusivity – and what’s needed to make good on this promising trend. Hosted on Acast. See acast.com/privacy for more information.…

1
How Patient Connect addresses unmet needs at the point of care 22:32

2+ y ago22:32

22:32

In this episode of Conversations in Healthcare, Mike Ward speaks with Dr. Grace Lomax, Clinical Director at Patient Connect, a part of Clarivate. Grace’s experience as a physician highlighted numerous unmet needs beyond just clinical issues – especially around healthcare literacy, education at the point of care, adherence and more. She discusses ho…

1
Social determinants: barriers to healthcare impacting racial and ethnic minorities 45:59

2+ y ago45:59

45:59

In this episode of Conversations in Healthcare, Matthew Arnold, Principal Analyst at Clarivate speaks with Dr. Kenton Johnston, Associate Professor of Health Management and Policy at Saint Louis University about disparities in the US health system. Matthew and Ken discuss both the historical context as well as the evolution of the system since the …

1
How Novo Ventures prioritized their investment strategy during the pandemic 25:50

3y ago25:50

25:50

In this episode of Conversations in Healthcare, Mike Ward speaks with Naveed Saddiqi, Senior Partner at Novo Ventures, one of the largest venture capital groups in the life sciences sector. Naveed shares about the firm’s mandate to generate funds for the Novo Nordisk Foundation, how the pandemic impacted their investment strategy and what excites h…

1
How Healx uses AI to transform rare disease drug discovery 27:52

3y ago27:52

27:52

In this episode of Conversations in Healthcare, Mike Ward speaks with Dr. Tim Guilliams, the co-founder and CEO of Healx. Healx is an artificial intelligence-powered technology company that's dedicated to helping rare disease patients access life improving treatments. Mike and Tim discuss the company’s innovative approach to drug discovery, choosin…

1
How the pandemic shifted Roche’s priorities and R&D investments 31:20

3y ago31:20

31:20

In this episode of Conversations in Healthcare, Mike Ward speaks with Richard Erwin, general manager and managing director of Roche Products Limited (UK), which was recorded in collaboration with One Nucleus's ON Helix conference (June 2021). Richard shares how the pandemic has shifted Roche’s priorities and why the organization has heavily increas…

1
Optimizing patient-first clinical trials with advanced site intelligence 40:56

3y ago40:56

40:56

In this episode of Conversations in Healthcare, Mike Ward speaks with Oriol Serra, former Head of Site Intelligence and Selection at Pfizer and Simon Andrews, Vice President of RWD Engagements and Innovations at Clarivate about optimizing patient-first clinical trial design and ensuring trial groups align to real-life populations and needs. The gro…

1
Showing the value of regulatory intelligence in pharma 31:32

3y ago31:32

31:32

In this episode of Conversations in Healthcare, Mike Ward speaks with Carolyn Hynes, Director of Regulatory Intelligence at AstraZeneca, and Céline Rodier, Senior Health Policy Manager at Clarivate, about strategies and tools to gather and assess regulatory intelligence, as well as KPIs and approaches to demonstrating ROI within your organization. …

1
Overcoming health inequity in the U.S. and the role of telehealth: Ideas and best practices from Cigna, Henry Ford Health System and the eHealth Initiative 36:46

3y ago36:46

36:46

Increased reliance on telehealth services has been one of the most significant care delivery shifts prompted by the COVID-19 pandemic. However, the pandemic has also thrown more light on the challenges of health inequity in the United States, especially among African American and Hispanic communities. We discuss these issues and potential solutions…

1
Best practices for university - healthcare partnerships: Learnings from the Institute of Cancer Research 27:59

3y ago27:59

27:59

In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Dr. Toby Richardson, who is Head of Business Development and Licensing; Deputy Director of Business and Innovation at The Institute of Cancer Research. Mike and Toby discuss how research collaborations betwee…

1
Best practices for university – healthcare partnerships: Learnings from Oxford 35:15

3+ y ago35:15

35:15

In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Dr. Phil Clare, the Deputy Director, Research Services (Knowledge Exchange and Engagement) at the University of Oxford. Mike and Dr. Clare discuss the key role that university research plays in shaping new me…

1
The evolution of the asset-centric approach in biotech venture capital 47:29

3+ y ago47:29

47:29

In this episode of Conversations in Healthcare, Mike Ward, Head of Thought Leadership, Life Sciences and Healthcare at Clarivate, speaks with Francesco De Rubertis, a co-founder and managing partner at Medicxi, one of the most prominent financial supporters of innovative biotech activity. Francesco provides insights into how the biotech venture cap…

1
Drugs to Watch 2021 23:50

3+ y ago23:50

23:50

Clarivate market experts break down the opportunities and potential threats for 2021’s Drugs to Watch – the key drugs expected to be blockbusters by 2026. Hosted on Acast. See acast.com/privacy for more information.

1
Utilizing pluripotent stem cells in cell therapy 25:55

4y ago25:55

25:55

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Brian Culley, CEO of Lineage Cell Therapeutics. Brian and Mike discuss the company’s cell therapy program, utilizing pluripotent stem cells, initially targeting dry age-related macular degeneration, acute spinal cord i…

1
The past, present and future of next generation sequencing 30:07

4y ago30:07

30:07

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Nick McCooke, CEO of Longas Technologies. Having been at the forefront of developing next generation sequencing, Nick talks to Mike about his past work, current projects and future predictions for this key technology in …

1
COVID-19, multi-stem clinical trials and a new way of fundraising 50:05

4y ago50:05

50:05

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership talks to Gil Van Bokkelen, founder, chairman and CEO of Athersys Inc. They discuss the company’s clinical program that is focusing on a special class of stem cells which display very unique properties and have been obtained from healthy young consenting don…

1
Early planning key to successful access and product launch 29:35

4y ago29:35

29:35

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, speaks with Alison Kneen, Senior Vice President, Global Market Access and Head of the Centre of Innovation and Regulatory Science (CIRS) and DRG Abacus. Learn why early and thorough planning is so important for a successful product launch, and how A…

1
Transforming the treatment of cancer with oncolytic viruses 33:06

4y ago33:06

33:06

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, speaks with Stephen Russell, CEO of Vyriad. Dr. Russell reveals invaluable insights for those looking for or currently putting together partnership deals. Stephen shares his journey from academia at the Mayo Clinic to founding Vyriad, and eventually…

1
Possible treatment for COVID-19 related respiratory failure 21:37

4y ago21:37

21:37

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Jonathan Javitt, CEO of NeuroRx. Dr Javitt discusses how NeuroRx is working in collaboration with Relief Therapeutics on Aviptadil, a synthetic version of vasoactive intestinal peptide, and a potential treatment of COV…

1
Pivoting a product launch during the pandemic 35:23

4y ago35:23

35:23

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Bryan Witherbee, President & CEO of Adarza BioSystems. Earlier this year, Adarza raised 25 million dollars to support the full commercialization of Ziva, an automated biological platform which delivers comprehensive, h…

1
How Glympse Bio oversubscribed their Series B funding amidst the pandemic 44:12

4y ago44:12

44:12

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Dr. Caroline Loew, President and CEO from Glympse Bio. They discuss the biotech’s focus on both disease detection and response to treatment using bioengineered sensors, starting with NASH. Dr. Loew also shares career a…

1
A novel approach to treating neurodegenerative disease 26:19

4y ago26:19

26:19

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, part of Clarivate, speaks with Dr. Leen Kawas, president and CEO of Athira Pharma. Dr. Kawas shares the company’s innovative approach to treating Alzheimer’s disease by developing small molecules to restore neuronal health and stop neurodegeneration…

1
An update from biopharma’s hotspot 27:26

4y ago27:26

27:26

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, Part of Clarivate talks to Bob Coughlin, president and CEO of the Massachusetts Biotechnology Council. Bob provides insights from what is unarguably the world’s number one biopharma hotspot. Bob and Mike discuss how the industry…

1
Addressing strategic challenges for biotech companies 30:55

4y ago30:55

30:55

In this episode of Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, talks to Dr Srikanth Rajagopal (or Doc, as he is fondly referred to). Doc, a partner at DRG Consulting, whose areas of expertise include product and portfolio strategy to name a few, chatted to us about common strategic challenges biotechnology comp…

1
Collaborating with officials to continue developments 39:08

4y ago39:08

39:08

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Joe Panetta, President and CEO of BIOCOM. Joe talks around how BIOCOM has worked closely with government officials to ensure the life science community can continue to function throughout the COVID-19 pandemic, and how t…

1
How including patients can help with the fight against Parkinson’s Disease 21:27

4y ago21:27

21:27

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Charlotte Allen and Russ Bradford from Parkinson’s Concierge. Russ and Charlotte offer a unique insight into how being a patient centric organisation enables them to help the Parkinson’s Disease community improve their q…

1
Maximising R+D efforts through better epidemiology understanding 23:13

4y ago23:13

23:13

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, talks to Mike Hughes, Senior Director of Epidemiology at DRG. With epidemiology entering our daily vernacular, thanks to the Covid-19 pandemic, Mike gives a definition of what it is, the approaches used to model epidemiology ass…

1
Bringing together minds to combat COVID-19 27:01

4y ago27:01

27:01

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG talks to Sir Mene Pangalos, Executive Vice President at AstraZeneca. Sir Mene talks to Mike about AstraZeneca's learnings from helping Chinese colleagues combat Coronavirus at the end of 2019, and then expanding input as it becam…

1
An unprecedented time of scientific innovation 39:27

4y ago39:27

39:27

In this fireside chat brought to you by Conversations in Healthcare, Mike Ward, Global Head of Thought Leadership at DRG, talks to Houman Ashrafian, Managing Partner at SV Health Investors. Houman gives an interesting perspective into how and why biotech investment has remained robust throughout the Covid-19 pandemic. He talks to Mike about his pro…

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