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#18 DKK3 - finally a biomarker of ongoing kidney injury, with Danilo Fliser
Manage episode 423389642 series 3548026
Sisällön tarjoaa European Renal Association. European Renal Association tai sen podcast-alustan kumppani lataa ja toimittaa kaiken podcast-sisällön, mukaan lukien jaksot, grafiikat ja podcast-kuvaukset. Jos uskot jonkun käyttävän tekijänoikeudella suojattua teostasi ilman lupaasi, voit seurata tässä https://fi.player.fm/legal kuvattua prosessia.
Every nephrologist knows about serum creatinine, eGFR, albuminuria, proteinuria. We use them to assess disease activity. But do we really assess disease activity with them? eGFR can be low and albuminuria or proteinuria can be high because of chronic and potentially irreversible changes, like glomerulosclerosis and tubulointerstitial fibrosis, changes that might not be amenable to treatment. How do we know which patient needs more treatment if what we are picking up with established markers might be fibrosis. Well, these questions might become old-fashioned quickly. Let us introduce you to DKK3, a new urine biomarker which could finally identify patients with ongoing kidney injury that might benefit from more treatment. Have a listen to our new ERA podcast with Danilo Fliser, explaining what DKK3 is and why we should all probably begin measuring it.
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