Episode 17. Acquired Aplastic Anemia

Blood Cancer Talks

Sisällön tarjoaa Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff. Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff tai sen podcast-alustan kumppani lataa ja toimittaa kaiken podcast-sisällön, mukaan lukien jaksot, grafiikat ja podcast-kuvaukset. Jos uskot jonkun käyttävän tekijänoikeudella suojattua teostasi ilman lupaasi, voit seurata tässä https://fi.player.fm/legal kuvattua prosessia.

1+ y ago 46:29

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In this episode, we discuss the management of acquired aplastic anemia with Dr. Amy DeZern. Here are the links to some of the key articles discussed in this show:

1. Review article on aplastic anemia:

https://www.nejm.org/doi/10.1056/NEJMra1413485

2. RCTs testing whether addition of cyclosporine to ATG improves outcomes in aplastic anemia:

https://www.nejm.org/doi/10.1056/NEJM199105093241901

https://www.sciencedirect.com/science/article/pii/S0006497120489748

3. RCT testing horse versus rabbit ATG in aplastic anemia:

https://www.nejm.org/doi/full/10.1056/nejmoa1103975

4. Single-arm study of eltrombopag in addition to standard immunosuppressive therapy in aplastic anemia:

https://www.nejm.org/doi/10.1056/NEJMoa1613878

5. Long-term follow up of patients treated with immunosuppressive therapy and eltrombopag:

https://ashpublications.org/blood/article/139/1/34/476916

6. RACE Trial: Standard immunosuppressive therapy +/- eltrombopag in aplastic anemia:

https://www.nejm.org/doi/10.1056/NEJMoa2109965

7. Clinical and molecular determinants of clonal evolution in patients with aplastic anemia:

https://ascopubs.org/doi/abs/10.1200/JCO.22.00710

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