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Astrocytic GABA and Circadian Timekeeping
Manage episode 458782464 series 3602245
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Welcome to this episode of the Heliox Podcast! Ever wonder how your brain manages to keep time, waking you up without an alarm or syncing your daily rhythms? Today, we’re diving deep into cutting-edge research that flips the script on circadian biology.
Join us as we uncover the surprising role of astrocytes—those unsung heroes of the brain—and their production of GABA in orchestrating our internal clocks. This fascinating journey takes us through groundbreaking studies that challenge what we know about the brain’s master clock, the SCN, and explores how these discoveries could reshape our understanding of jet lag, sleep disturbances, and even conditions like Alzheimer’s.
Curious minds, let’s explore the hidden timekeepers at work in your brain!
A 'chemical metronome': Researchers uncover how astrocytes help the brain's master clock keep time
https://medicalxpress.com/news/2024-12-chemical-metronome-uncover-astrocytes-brain.html
More information: Natalie Ness et al, Rhythmic astrocytic GABA production synchronizes neuronal circadian timekeeping in the suprachiasmatic nucleus, The EMBO Journal (2024). DOI: 10.1038/s44318-024-00324-w
Rhythmic astrocytic GABA production synchronizes neuronal circadian timekeeping in the suprachiasmatic nucleus
https://www.embopress.org/doi/full/10.1038/s44318-024-00324-w
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